By 2007, the Legacy of Kain series had collectively sold over 3.5 million copies, but its commercial success has varied with each game.[127] Blood Omen surpassed Crystal Dynamics' expectations,[3][7] with reported sales figures ranging from 320,082 units to 2 million copies,[9] whereas Soul Reaver sold over 1.5 million copies, and was included on Sony's "Greatest Hits" list.[128][129] Soul Reaver 2 and Blood Omen 2 also performed well, selling in excess of 500,000 copies each and becoming Greatest Hits titles.[30][92][130] Defiance sold between 500,000 and 1 million units, but failed to live up to Eidos's sales targets.[34]

The series takes place in the fictional land of Nosgoth—a gothic fantasy setting—and revolves around Kain's quest to defy his fate and restore balance to the world. Legacy of Kain: Soul Reaver introduced another antihero protagonist, Raziel; the adventures of both characters culminate in Legacy of Kain: Defiance. Themes of destiny, free will, morality, redemption and the hero's journey recur in the storyline, which was inspired by ancient literature, horror fiction, Shakespeare's plays and Gnosticism. The Legacy of Kain games have enjoyed critical success, particularly receiving praise for high-quality voice acting, narrative, and visuals, and, as a whole, had sold over 3.5 million copies as of 2007. In 2015, a sequel has been confirmed as "50/50".[1]